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    Methods and their possible consequences. Advances to avoid side effects.

    Wrinkles
    Expression wrinkles: during the first two or three decades of life of a human being expression wrinkles are so thin they are barely visible. Over time, wrinkles multiply and become deeper. This is normal. Yet many times wrinkles are considered as an imperfection and many people try to break free of them with injections in the lines, for example. This method can have unpleasant side effects, especially when the treatment was long and the wrong filling material (filler) was used.

    In the early days of the hypodermic injection against wrinkles, in the 50s and 60s, paraffinic oil and liquid silicone were used. Currently, this is forbidden in our country, because it involves many dangers, such as severe infections, deformities or allergies, according to the general secretary of the German Association of Aesthetic Surgery. There is also the risk that may generate tissue growths and nodules shaped ulcers.

    Subsequently, permanent fillers were developed to a lasting wrinkles removal. They are injectable collagen implants and hyaluronic acid, which do not contain, at microscopic level, plastic particles. These methods are efficient because they activate the protection mechanism of the body to foreign bodies so it encapsulates foreign bodies, which may result in an increase in volume and smoothing.

    However, after the initial “boom”, these products just are scarcely used today, because of their proven risks: Short or long term almost always problems arise, starting with a formation of ugly nodules or the implant displacement causing later infections and allergies and as late effect, ulcers.

    Even when the implant has integrated well on the body and has had the desired effect, the result is not always lasting. In many cases, years later, may arise unwanted tissue reactions or deformations. As the body cannot break down the plastic particles that are contained in the permanent fillers, the problems they generate often only end when removing them.

    Usually just injecting drugs such as cortisone to dissolve the particles is enough. However, often there is no choice but to remove them by surgery. It is a laborious process and the result, from the aesthetic point of view, is sometimes very unsatisfactory.
    Today there are a number of much less harmful materials for hypodermic injection against wrinkles. They are made in part biologically and partly industrially and are distinguished by their efficiency and durability. The material most used is hyaluronic acid, which is a sugar molecule that is part of human skin.

    A few years ago, that acid displaced another substance of first place in the list of wrinkle materials: collagen, a protein produced by the human body itself. This is because the treatment of wrinkles with collagen usually produces allergic, sometimes strong, reactions because the protein molecules used are obtained from the skin of swine or cattle and causes intolerance in some individuals.

    Being biologically degradable substances, hyaluronic acid and collagen are gradually resorbed completely by the body. Therefore, the smoothing effect at some point decreases, so it must be reactivated with a new hypodermic injection.